Skin Cancer Treatment

High risk
Mohs surgery or Wide excision Click the link to see the differences between Mohs VS Wide Excision Radiation in case of non-surgical candidate Systemic therapy in case of nodal or distant metastasis

Option	Advantages	Disadvantages	5-year Recurrence rate
Low risk
Standard wide excision	Have histologic margin assessment	May need re-excision or Mohs surgery, if pathology report positive margin	BCC:0.8-17.4% SCC:5-8%
Shave removal	Fast &Low cost Not require suture	Inadequate margin assessment	BCC:0.5-30% SCC-not recommend
Electrodesiccation & Curettage	Fast &Low cost Not require suture	No histologic margin assessment	BCC: 1.2-40% SCIS:3-8% SCC: not enough report
Cryotherapy	Fast &Low cost Not require suture	No histologic margin assessment Multiple session requirement	BCC:5-39% SCC: not enough report
Topical imiquimod	Lowest cost	Approved for superficial type BCC Need to apply at least 6 weeks Irritation	BCC: 11% by Gollnick et al, 2008 SCC: not enough report
Other modalities: 5-fluorouracil, photodynamic therapy, radiation